Everything you need for better enzymes

In silico services and specialty enzymes for boosting your industrial processes

Our services

Comprehensive enzyme discovery, optimization, experimental validation and project management services for pharmaceutical, biotech and other sustainable chemistry applications

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Our products

Ready-to-use, specialty enzymes for a wide number of applications. Find the right catalyst for your needs!

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Our services

EnzymeSearch (ES)

Identify the best enzymes for your needs

We use a combination of bioinformatics and 3D molecular modeling to identify your best target enzymes in the shortest possible time.

In SilicoDesign (ISD)

Improves your enzyme

Our multiscale protocol mimics natural directed evolution by combining bioinformatics, molecular modelling and quantum computing to custom design your enzyme, in less than 1 month.

AdditionalSupport

Diagnosis & Lab

We use our diagnostic tools to analyze the potential of your enzyme campaigns and rescue dead-end projects.

Samples of enzymes identified in any Enzyme Search or In Silico Design campaign are delivered to the client for in-house validation.

Enzymes tailored to your specific requirements

Activity

We can increase reaction rates by 30-700% in a single round of evolution testing 10-90 enzyme variants

Selectivity

We design a highly complementary active site so your enzyme is selective only to your target substrate, particularly useful if you’re looking for asymmetric synthesis.

Specificity

We can increase or reduce specificity to target new substrates of interest for your preferred enzyme.

Thermal &pH Stability

We improve temperature and pH stability profiles to make your biocatalytic processes more robust.

Tolerance tocomplex matrices

We improve enzyme stability in water/organic solutions and enzyme tolerance to complex matrices like detergents.

Our Products

ZA-ADH

Alcohol dehydrogenases

BASIC INFO

Alcohol Dehydrogenases (ADHs) (E.C. 1.1.1.x; x = 1 or 2, ADHs) are enzymes that perform the interconversion of alcohols and aldehydes/ketones reaction. They are widely used in the biocatalytic industry to reduce ketones into chiral alcohols.
Our new ZA-ADHs are wild type enzymes that are active on the desired substrates. Candidates have been carefully selected among millions of variants by our in silico technology ZYMEVOLVER.

USES

Conversion of ketone/aldehyde to alcohol
Conversion of alcohol to ketone/aldehyde
Chiral resolution of alcohol racemate
Production of desired chiral alcohol
Removal of undesired alcohol from reaction mix

ADDITIONAL INFO

The ZA-ADH Kit is for research use only, not for diagnostic or commercial use. All enzymes contained in the ZA-ADH Kit are property of Zymvol and Aminoverse, available for commercial licensing.

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