Everything you need for better enzymes
In silico services and specialty enzymes for boosting your industrial processes
Our services
Comprehensive enzyme discovery, optimization, experimental validation and project management services for pharmaceutical, biotech and other sustainable chemistry applications.
Our products
Ready-to-use, specialty enzymes for a wide number of applications. Find the right catalyst for your needs!
Download brochureOur services
EnzymeSearch
Identify the best enzymes for your needs with BIOMATCHMAKER®
We use a combination of bioinformatics and 3D molecular modeling to identify your best target enzymes in the shortest possible time.
In SilicoDesign
Improve your enzyme with ZYMEVOLVER
Our multiscale protocol mimics natural directed evolution by combining bioinformatics, molecular modelling and quantum computing to custom design your enzyme, in less than 1 month.
ZymQuest
Find new enzymes and improve them, all in one!
Includes improvement taking into account both active site and long-range positions; physical, ready-to-test in industrial setting enzymes; and shortened timelines due to seamless workflow.
ExperimentalValidation
Diagnosis & Lab
All your computational and experimental needs in one place.
Reduce project costs and meet tight deadlines by performing the experimental validation with our trusted partners.
Enzymes tailored to your specific requirements
Activity
We can increase reaction rates by 30-700% in a single round of evolution testing 10-90 enzyme variants.
Selectivity
We design a highly complementary active site so your enzyme is selective only to your target substrate, particularly useful if you’re looking for asymmetric synthesis.
Specificity
We can increase or reduce specificity to target new substrates of interest for your preferred enzyme.
Thermal &pH Stability
We improve temperature and pH stability profiles to make your biocatalytic processes more robust.
Tolerance tocomplex matrices
We improve enzyme stability in water/organic solutions and enzyme tolerance to complex matrices like detergents.
Our products
ZA-ADH KITS
Alcohol Dehydrogenases
BASIC INFO
Alcohol Dehydrogenases (ADHs) (E.C. 1.1.1.x; x = 1 or 2, ADHs) are enzymes that perform the interconversion of alcohols and aldehydes/ketones reaction. They are widely used in the biocatalytic industry to reduce ketones into chiral alcohols.
Our new ZA-ADHs are wild type enzymes that are active on the desired substrates. Candidates have been carefully selected among millions of variants by our in silico technology ZYMEVOLVER.
USES
Conversion of ketone/aldehyde to alcohol
Conversion of alcohol to ketone/aldehyde
Chiral resolution of alcohol racemate
Production of desired chiral alcohol
Removal of undesired alcohol from reaction mix
ADDITIONAL INFO
The ZA-ADH Kit is for research use only, not for diagnostic or commercial use. All enzymes contained in the ZA-ADH Kit are property of Zymvol and Aminoverse, available for commercial licensing.